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1,142 results on '"Meador, Kimford J."'

5. Highlights From the Annual Meeting of the American Epilepsy Society 2022

Author

Valencia, Ignacio, primary, Alexander, Allyson L., additional, Andrade, Danielle M., additional, Arevalo-Astrada, Miguel, additional, Rubiños, Clio, additional, Auer, Nancy, additional, Bainbridge, Jacquelyn L., additional, Baxendale, Sallie A., additional, Bartolomei, Fabrice, additional, Becker, Danielle A., additional, Berg, Anne T., additional, Bernasconi, Andrea, additional, Bernasconi, Neda, additional, Bernhardt, Boris, additional, Bhatnagar, Shivani, additional, Blümcke, Ingmar, additional, Blumenfeld, Hal, additional, Buchanan, Gordon F., additional, Burdette, David E., additional, Burneo, Jorge G., additional, Busch, Robyn M., additional, Chauvel, Patrick, additional, Chin, Jeannie, additional, Clifford, Lisa, additional, Conner, Kelly R., additional, Cook, Mark J., additional, Conway, Jeannine, additional, Diaz-Arastia, Ramon, additional, Drees, Cornelia, additional, French, Jacqueline A., additional, Ganguly, Taneeta Mindy, additional, Gelfand, Michael A., additional, Glauser, Tracy A., additional, Gleichgerrcht, Ezequiel, additional, Goldman, Alica M., additional, Gonzalez-Martinez, Jorge, additional, Gotman, Jean, additional, Grinspan, Zachary, additional, Guilfoyle, Shanna, additional, Gupta, Gita, additional, Hammer, Michael, additional, Hartman, Adam L., additional, Hentges, Katie, additional, Hogan, R. Edward, additional, Huh, Linda, additional, Hyslop, Ann, additional, Jobst, Barbara, additional, Josephson, Colin B., additional, Kelley, Sarah A., additional, Knupp, Kelly, additional, Koepp, Matthias, additional, Kothare, Sanjeev V., additional, Krook-Magnuson, Esther, additional, Kwasa, Jasmine, additional, La Vega-Talbott, Maite, additional, Lam, Alice D., additional, Lee, Jong Woo, additional, Lowenstein, Daniel H., additional, Maturu, Sarita, additional, Mayor, Luis Carlos, additional, McDonald, Carrie, additional, McKee, Heather R., additional, McKhann, Guy M., additional, Meador, Kimford J., additional, Mefford, Heather C., additional, Michael, Elizabeth H., additional, Mikati, Mohamad A., additional, Millichap, John J., additional, Mitchell, James W., additional, Myers, Leah S., additional, Naritoku, Dean, additional, Neville, Kerri L., additional, Noebels, Jeffrey, additional, O’Brien, Terence J., additional, Oluigbo, Chima O., additional, Patel, Anup D., additional, Pavlova, Milena K., additional, T. Paz, Jeanne, additional, Pennell, Page B., additional, Perry, M. Scott, additional, Perucca, Piero, additional, Pitkänen, Asla, additional, Plueger, Madona, additional, Pugh, Mary Jo, additional, Quigg, Mark, additional, Reddy, Shilpa B., additional, Ryan, Christopher, additional, Reynolds, Tamara S., additional, Sajatovic, Martha, additional, Santana-Gomez, Cesar, additional, Schommer, Linsday, additional, Schuele, Stephan, additional, Shellhaas, Renée A., additional, Shrey, Daniel W., additional, Singh, Rani K., additional, Sperling, Michael R., additional, Suleman, Saher, additional, Templer, Jessica W., additional, Thom, Maria, additional, Trinka, Eugen, additional, Varadkar, Sophia M., additional, Velez-Ruiz, Naymee, additional, Velíšková, Jana, additional, Voskobiynyk, Yuliya, additional, Wagner, Janelle L., additional, Wagnon, Jacy L., additional, Waller, Claire, additional, Waller, Jill, additional, Wang, Zhong Irene, additional, Welborn, Michelle W., additional, and Wirrell, Elaine, additional

Published
2023
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6. Cognitive outcomes at age 3 years in children with fetal exposure to antiseizure medications (MONEAD study) in the USA: a prospective, observational cohort study

Author

Meador, Kimford J, primary, Cohen, Morris J, additional, Loring, David W, additional, Matthews, Abigail G, additional, Brown, Carrie, additional, Robalino, Chelsea P, additional, Birnbaum, Angela K, additional, Voinescu, Paula E, additional, Kalayjian, Laura A, additional, Gerard, Elizabeth E, additional, Gedzelman, Evan R, additional, Hanna, Julie, additional, Cavitt, Jennifer, additional, Sam, Maria, additional, French, Jacqueline A, additional, Hwang, Sean, additional, Pack, Alison M, additional, and Pennell, Page B, additional

Published
2023
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7. Unjustified allegation on cancer risks in children of mothers with epilepsy taking high‐dose folic acid during pregnancy—No proof of a causal relationship

Author

von Wrede, Randi, primary, Witt, Juri‐Alexander, additional, Auvin, Stéphane, additional, Devlin, Anita, additional, Lagae, Lieven, additional, Marson, Anthony, additional, Meador, Kimford J., additional, O'Brien, Terence J., additional, Park, Jun, additional, Surges, Rainer, additional, Trinka, Eugen, additional, Wiebe, Samuel, additional, and Helmstaedter, Christoph, additional

Published
2023
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20. Mood and Anxiety Disorders and Suicidality in Patients With Newly Diagnosed Focal Epilepsy: An Analysis of a Complex Comorbidity

Author

Kanner, Andres M., Saporta, Anita S, Kim, Dong H, Barry, John J, Altalib, Hamada, Omotola, Hope, Jette, Nathalie, OʼBrien, Terence J., Nadkarni, Siddhartha, Winawer, Melodie R., Sperling, Michael, French, Jacqueline A, Abou-Khalil, Bassel, Alldredge, Brian, Bebin, Martina, Cascino, Gregory D, Cole, Andrew J., Cook, Mark J., Detyniecki, Kamil, Devinsky, Orrin, Dlugos, Dennis, Faught, Edward, Ficker, David, Fields, Madeline, Gidal, Barry, Gelfand, Michael, Glynn, Simon, Halford, Jonathan J., Haut, Sheryl, Hegde, Manu, Holmes, Manisha G., Kalviainen, Reetta, Kang, Joon, Klein, Pavel, Knowlton, Robert C, Krishnamurthy, Kaarkuzhali, Kuzniecky, Ruben, Kwan, Patrick, Lowenstein, Daniel H., Marcuse, Lara, Meador, Kimford J., Mintzer, Scott, Pardoe, Heath R, Park, Kristen, Penovich, Patricia, Singh, Rani K, Somerville, Ernest, Szabo, Charles A, Szaflarski, Jerzy P., Lin Thio, K. Liu, Trinka, Eugen, and Burneo, Jorge G

Published
2022
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27. Superior Verbal Memory Outcome After Stereotactic Laser Amygdalohippocampotomy

Author

Drane, Daniel L., primary, Willie, Jon T., additional, Pedersen, Nigel P., additional, Qiu, Deqiang, additional, Voets, Natalie L., additional, Millis, Scott R., additional, Soares, Bruno P., additional, Saindane, Amit M., additional, Hu, Ranliang, additional, Kim, Michelle S., additional, Hewitt, Kelsey C., additional, Hakimian, Shahin, additional, Grabowski, Thomas, additional, Ojemann, Jeffrey G., additional, Loring, David W., additional, Meador, Kimford J., additional, Faught, Edward, additional, Miller, John W., additional, and Gross, Robert E., additional

Published
2021
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29. The Obstetrical Care and Delivery Experience of Women with Epilepsy in the MONEAD Study.

Author

McElrath, Thomas F., Druzin, Maurice, Van Marter, Linda J., May, Ryan C., Brown, Carrie, Stek, Alice, Grobman, William, Dolan, Mary, Chang, Patricia, Flood-Schaffer, Kellie, Parker, Lamar, Meador, Kimford J., and Pennell, Page B.

Subjects
EPILEPSY in pregnancy, CESAREAN section, DELIVERY (Obstetrics), MATERNAL health services, ACADEMIC medical centers, RESEARCH funding, SCIENTIFIC observation, PREGNANT women, DESCRIPTIVE statistics, LABOR (Obstetrics), RESEARCH, PREGNANCY complications, ANTICONVULSANTS
Abstract

Objective We examined mode of delivery among pregnant women with epilepsy (PWWE) versus pregnant controls (PC). We hypothesize that PWWE are more likely to deliver by cesarean. Study Design The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study is an observational, prospective, multicenter investigation of pregnancy outcomes funded by the National Institute of Health (NIH). MONEAD enrolled patients from December 2012 through January 2016. PWWE were matched to PC in a case:control ratio of 3:1. This analysis had 80% power to detect a 36% increase in cesarean frequency assuming a baseline rate of 30% among PC at an α = 0.05. Results This report analyzed 331 PWWE (76%) and 102 PC (24%) who gave birth while enrolled in the study. PWWE and PC had similar rates of cesarean delivery (34.7 vs. 28.6%; p = 0.27). Of women with cesarean, rates of cesarean without labor were similar between groups for those delivering in recruitment hospitals (48.2 vs. 50.0%) but in nonrecruitment hospitals, cesarean rates without labor were over two-fold higher among PWWE than those of PC (68.8 vs. 30.8%; p = 0.023). Receipt of a cesarean after labor did not differ for PWWE compared to PC or by type of antiepileptic drug among the PWWE. Conclusion These findings suggest that the obstetrical experiences of PWWE and PC are similar. An interesting deviation from this observation was the mode of delivery with higher unlabored cesarean rates occurring among PWWE in nonrecruitment hospitals. As the study recruitment hospitals were tertiary academic centers and nonrecruitment hospitals tended to be community-based institutions, differences in perinatal expertise might contribute to this difference. Key Points Unlabored cesarean rates higher among women with epilepsy. Provider preference may influence delivery mode among women with epilepsy. Type and amount of antiepileptic drug was not associated with mode of delivery. [ABSTRACT FROM AUTHOR]

Published
2024
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30. Which terms should be used to describe medications used in the treatment of seizure disorders? An ILAE position paper.

Author

Perucca, Emilio, French, Jacqueline A., Aljandeel, Ghaieb, Balestrini, Simona, Braga, Patricia, Burneo, Jorge G., Felli, Augustina Charway, Cross, J. Helen, Galanopoulou, Aristea S., Jain, Satish, Jiang, Yuwu, Kälviäinen, Reetta, Lim, Shih Hui, Meador, Kimford J., Mogal, Zarine, Nabbout, Rima, Sofia, Francesca, Somerville, Ernest, Sperling, Michael R., and Triki, Chahnez

Subjects
SEIZURES (Medicine), DRUGS, DIRECT action, MEDICAL care, DISEASE progression
Abstract

A variety of terms, such as "antiepileptic," "anticonvulsant," and "antiseizure" have been historically applied to medications for the treatment of seizure disorders. Terminology is important because using terms that do not accurately reflect the action of specific treatments may result in a misunderstanding of their effects and inappropriate use. The present International League Against Epilepsy (ILAE) position paper used a Delphi approach to develop recommendations on English‐language terminology applicable to pharmacological agents currently approved for treating seizure disorders. There was consensus that these medications should be collectively named "antiseizure medications". This term accurately reflects their primarily symptomatic effect against seizures and reduces the possibility of health care practitioners, patients, or caregivers having undue expectations or an incorrect understanding of the real action of these medications. The term "antiseizure" to describe these agents does not exclude the possibility of beneficial effects on the course of the disease and comorbidities that result from the downstream effects of seizures, whenever these beneficial effects can be explained solely by the suppression of seizure activity. It is acknowledged that other treatments, mostly under development, can exert direct favorable actions on the underlying disease or its progression, by having "antiepileptogenic" or "disease‐modifying" effects. A more‐refined terminology to describe precisely these actions needs to be developed. [ABSTRACT FROM AUTHOR]

Published
2024
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32. Association of Epilepsy and Severe Maternal Morbidity

Author

Panelli, Danielle M., primary, Leonard, Stephanie A., additional, Kan, Peiyi, additional, Meador, Kimford J., additional, McElrath, Thomas F., additional, Darmawan, Kelly F., additional, Carmichael, Suzan L., additional, Lyell, Deirdre J., additional, El-Sayed, Yasser Y., additional, Druzin, Maurice L., additional, and Herrero, Tiffany C., additional

Published
2021
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37. Vinpocetine, cognition, and epilepsy

Author

Meador, Kimford J., primary, Leeman-Markowski, Beth, additional, Medina, Alexandre E., additional, Illamola, Sílvia M., additional, Seliger, Jordan, additional, Novak, Gloria, additional, Lin, Christine, additional, Ivanisevic, Mirjana, additional, Razavi, Babak, additional, Marino, Susan, additional, Boyd, Alan, additional, and Loring, David W., additional

Published
2021
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43. Changes in Seizure Frequency and Antiepileptic Therapy during Pregnancy

Author

Pennell, Page B., French, Jacqueline A., May, Ryan C., Gerard, Elizabeth, Kalayjian, Laura, Penovich, Patricia, Gedzelman, Evan, Cavitt, Jennifer, Hwang, Sean, Pack, Alison M., Sam, Maria, Miller, John W., Wilson, Steffanie H., Brown, Carrie, Birnbaum, Angela K., and Meador, Kimford J.

Subjects
Distribution, Drug therapy, Psychological aspects, Dosage and administration, Company distribution practices, Anticonvulsants -- Dosage and administration, Epilepsy -- Distribution, Epilepsy -- Drug therapy, Pregnant women -- Psychological aspects
Abstract

The frequency of epileptic seizures from pregnancy to the peripartum period is compared to that during the postpartum period. Changes in the doses of antiepileptic drugs administered to pregnant women with epilepsy are also examined.

Published
2020

44. Prenatal Exposure to Opioids and Neurodevelopmental Disorders in Children: A Bayesian Mediation Analysis.

Author

Wang, Shuang, Puggioni, Gavino, Wu, Jing, Meador, Kimford J, Caffrey, Aisling, Wyss, Richard, Slaughter, Jonathan L, Suzuki, Etsuji, Ward, Kristina E, Lewkowitz, Adam K, and Wen, Xuerong

Subjects
HUMAN abnormalities, RETROSPECTIVE studies, PRENATAL exposure delayed effects, PREGNANCY outcomes, CHILD psychopathology, PREGNANCY complications, RESEARCH funding, FACTOR analysis, DESCRIPTIVE statistics, OPIOID analgesics, DATA analysis software, LONGITUDINAL method
Abstract

This study explores natural direct and joint natural indirect effects (JNIE) of prenatal opioid exposure on neurodevelopmental disorders (NDDs) in children mediated through pregnancy complications, major and minor congenital malformations, and adverse neonatal outcomes, using Medicaid claims linked to vital statistics in Rhode Island, United States, 2008–2018. A Bayesian mediation analysis with elastic net shrinkage prior was developed to estimate mean time to NDD diagnosis ratio using posterior mean and 95% credible intervals (CrIs) from Markov chain Monte Carlo algorithms. Simulation studies showed desirable model performance. Of 11,176 eligible pregnancies, 332 had ≥2 dispensations of prescription opioids anytime during pregnancy, including 200 (1.8%) having ≥1 dispensation in the first trimester (T1), 169 (1.5%) in the second (T2), and 153 (1.4%) in the third (T3). A significant JNIE of opioid exposure was observed in each trimester (T1, JNIE = 0.97, 95% CrI: 0.95, 0.99; T2, JNIE = 0.97, 95% CrI: 0.95, 0.99; T3, JNIE = 0.96, 95% CrI: 0.94, 0.99). The proportion of JNIE in each trimester was 17.9% (T1), 22.4% (T2), and 56.3% (T3). In conclusion, adverse pregnancy and birth outcomes jointly mediated the association between prenatal opioid exposure and accelerated time to NDD diagnosis. The proportion of JNIE increased as the timing of opioid exposure approached delivery. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Neonatal Outcomes in the MONEAD Study of Pregnant Women with Epilepsy

Author

Van Marter, Linda J., primary, Pennell, Page B., additional, Brown, Carrie, additional, Hartman, Adam L., additional, May, Ryan C., additional, McElrath, Thomas, additional, Ippolito, Dominic, additional, Meador, Kimford J., additional, Bagic, Anto, additional, Barkley, Gregory, additional, Cavitt, Jennifer, additional, DeWolfe, Jennifer, additional, French, Jacqueline, additional, Gedzelman, Evan, additional, Gerard, Elizabeth, additional, Hwang, Sean, additional, Kalayjian, Laura, additional, Krauss, Gregory, additional, Labiner, David, additional, McCabe, Paul, additional, Miller, John, additional, Pack, Alison, additional, Penovich, Patricia, additional, Sam, Maria, additional, Serrano, Enrique, additional, and Strickland, Suzanne, additional

Published
2021
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48. Pregnancy outcomes of refractory epilepsy patients treated with Brain–responsive neurostimulation

Author

Li, Yi, primary, Eliashiv, Dawn, additional, LaHue, Sara C., additional, Rao, Vikram R., additional, Martini, Michael L., additional, Panov, Fedor, additional, Oster, Joel M, additional, Yoshii-Contreras, June, additional, Skidmore, Christopher T., additional, Kalayjian, Laura A., additional, Millett, David, additional, and Meador, Kimford J., additional

Published
2021
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